Thursday, January 25, 2018

BREAST CANCER

Breast cancer is when cancer starts in the breast. A Breast cancer is when cancer starts in the breast. Breast cancer (malignant breast neoplasm) from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk.     


TYPES OF BREAST CANCERS                

Tumours of the breast are believed to arise from terminal ductal lobular units and comprise two common morphological types (Russo & Russo, 1999). They are:
·                     Ductal Carcinoma
·                     Lobular Carcinoma

  • Cancers originating from originating from lobules are known as lobular carcinomas; those from ducts are known as ductal carcinomas.
  • In situ breast cancer- cancer cells remain confined within their place of origin and do not attack surrounding breast tissue. The term 'in situ' refers to pre-invasive breast cancer. This is breast cancer which has not yet penetrated ('invaded') through the basement membrane (the membrane at the base of the epithelial lining of ducts or glands).
  • Invasive or metastatic breast cancer- cancer cells break free of their place of origin and spread to different parts of the body. In situ carcinoma has the potential to become invasive carcinoma, and so is treated as an early form of breast cancer. 


DUCTAL CARCINOMAS
About 80-90% of all breast cancers are ductal in origin. The ducts in the breast carry milk from the lobules or glands of the breast to the nipples.
There are two types of Ductal carcinomas. They are:
  • Ductal carcinoma in situ (DCIS)
  • Invasive Ductal Carcinoma (IDC)
 Ductal carcinoma in situ (DCIS)
Ductal carcinoma in situ (DCIS; also known as intraductal carcinoma) is the most common type of non-invasive breast cancer. DCIS means that the cancer cells are inside the ducts but have not spread through the walls of the ducts into the surrounding breast tissue.
A mammogram is often the best way to find DCIS early.


FIG-1: In the left-hand image above, the normal cells which line the ducts of the breast might look. In ductal carcinoma in situ (DCIS, the image to the right), the duct cells have developed the ability to multiply out of control - one of the characteristics of cancer. The cancerous cells are filling the duct but have not yet spread beyond the lining of the duct. This is known as DCIS.

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